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Indications Myoflex Cream.
Myoflex Cream Symptomatic treatment of muscular pain caused by muscle spasticity.
Contraindications Myoflex Cream.
Hypersensitivity to tiokolhikozydu or colchicine, muscle hypotonia, flaccid paralysis.
Dosage Myoflex Cream.
For external use only.
The cream should be applied to adults of two or three times a day, covering its entire area of skin lesions at the site.
Adverse reactions Myoflex Cream.
Rarely could experience skin reactions such as rash, swelling, allergic reactions and psevdoalerhichni (allergic vasculitis).
Overdose Myoflex Cream.
On cases of overdose have been reported.
Use during pregnancy and lactation.
As appropriate well-controlled studies in pregnant women were not conducted, the drug should not be used during pregnancy.
Pharmacokinetic properties tiokolhikozydu studied enough, because during treatment with breast vyhoduvannya should be discontinued.
Children
Tiokolhikozyd not recommended for use in children.
Precautions Myoflex Cream.
In case of hypersensitivity reactions or the appearance of irritation, the drug should be discontinued.
Influence on ability to drive a car or operating other machinery.
Unknown.
Interaction with other medicinal products and other forms of interaction.
Cases of drug interactions are unknown.
Be careful while using drugs with similar properties (eg, oral or parenteral muscle relaxants).
Pharmacological propertiesMyoflex Cream.
Pharmacodynamics.
Semi-synthetic muscle relaxants, a derivative of natural glycosides – kolhikozydu.
In preclinical studies of the drug revealed selective affinity for gamma-amino butyric acid (GABA) receptors and hlitsynerhichnymy. Assumed that the relaxing effect on muscles caused by direct activation of GABA receptor at the spinal cord, which promotes relaxation of skeletal muscles.
Hlitsynomimetychna tiokolhikozydu effect observed at different levels of the nervous system. Due to these properties, he removes the spastic syndrome in rheumatic diseases or injuries, and spastic syndrome, damage the central nervous system.
The drug does not Curariform action. It does not cause paralysis of the final division of the motor nerve does not affect the respiratory system. In addition, the drug has no effect on the cardiovascular system.
Pharmacokinetics.
Data on the pharmacokinetic properties tiokolhikozydu enough.
Pharmaceutical characteristics.
Basic physical and chemical properties:
homogeneous cream yellow.
